This is the Primordial Web Page for the course Origins of Life 3D03

Dr Ralph Pudritz and Dr Paul Higgs

Course Outline -   PDF


PDF Papers to download

These papers are complementary to the lectures or the assignments.

Miller and Lazcano (1995) - The Origin of Life - Did it Occur at High Temperatures?   PDF

Islas et al. (2003) - Hyperthermophily and the origin and earliest evolution of life   PDF

Whittet (1997) - Is extraterrestrial organic matter relevant to the origin of life on earth?   PDF

Gribbin and Rees "Cosmic Coincidences" - Tailor-made for man?   PDF

Orgel (2004) - Prebiotic chemistry and the origin of the RNA world   PDF

Joyce (2002) - The antiquity of RNA-based evolution   PDF

Jeffares, Poole and Penny (1998) - Relics from the RNA world   PDF

Segre and Lancet (2000) - Composing Life   PDF

Eigen, McCaskill and Schuster (1988) - Molecular Quasispecies   PDF

Nowak and May (1992) - Evolutionary Games and Spatial Chaos   PDF

Szabo et al (2002) - Replicators with limited dispersal evolve towards higher efficiency and fidelity   PDF

Szathmary et al (2005) - The evolutionary potential and requirements for minimal protocells   PDF

Castresana (2001) - Comparative genomics and bioenergetics   PDF

Olson and Blankenship (2004) - Thinking about the evolution of photosynthesis   PDF

Rothschild and Mancinelli (2001) - Life in extreme environments   PDF

Schopf (2006) - Fossil evidence of Archaean life   PDF

Brasier et al (2006) - A fresh look at the fossil evidence for early Archaean cellular life   PDF


Origins Institute Book

Link to the book web page

All the chapters are worth looking at and can be downloaded from the book web page.

PLEASE READ the following two chapters carefully because we are intending to have a class discussion on these.

Deamer - Emergent phenomena in biology: the origin of cellular life.

McKay - The search for life on Mars


Lecture notes to download

The powerpoint show should open in the Internet Explorer web browser.

Pudritz - Introduction   PPT

Pudritz - Cosmic Foundations   PPT

Higgs - Chemistry of Life   PPT

Pudritz - Stars   PPT

Pudritz - Star Formation   PPT

Pudritz - Planet Formation   PPT

Pudritz - Earth History   PPT

Higgs - RNA World   PPT

Higgs - Theoretical Models   PPT

Higgs - Thermodynamics   PPT

Higgs - Metabolism   PPT

Pudritz - Mars   PPT

Pudritz - Europa   PPT

Higgs - Fossils   PPT

Higgs - Phylogenetics   PPT

EXCELLENT FOR REVISION - Astrobiology Primer   PDF


Assignments to download

Pudritz - Assignment 1 - due by Oct 3rd (worth 10%)   PDF

Pudritz - Assignment 2 - due by Oct 20th (worth 10%)   PDF

Higgs - Assignment 3 - due by Oct 31st (worth 10%)   DOC

Mid-term test - Tue 7th Nov (worth 15%)

Higgs - Assignment 4 - due by Nov 24th (worth 10%)   DOC   ANSWERS DOC

Last lecture - 1st Dec

Final exam - Fri 8th Dec (worth 45%)


Extra interesting stuff

These papers are relevant but we will not expect you to know the details for the exam.

Weber and Miller (1981) - Reasons for the occurrence of the 20 coded protein amino acids   PDF

Gogarten and Taiz (1992) - The evolution of proton pumping ATPases: Rooting the tree of life   PDF

Gupta and Golding (1996) - The origin of the eukaryotic cell   PDF

Roger and Hug (2006) - The origin and diversification of eukaryotes   PDF